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Worsening mortality among working-age adults is a significant concern in the United States. Because rising mortality is an indicator of deteriorating population health among adults, it is important to investigate the underlying causes and their implications. At the request of the National Institute on Aging, the Committee on Population of the National Academies convened a workshop to examine what is currently known about trends in disability and disabling morbidity, with the goal for helping to set a research agenda and data priorities. This publication summarizes the presentations and discussion of the workshop.