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Social determinants of health, including factors such as the conditions in which people are born, grow, work, live, and age; their education and income; and many other elements can influence their likelihood of developing cancer, the type of cancer, the cancer stage at diagnosis, the quality of care they receive, and their health outcomes. The National Cancer Policy Forum hosted a workshop in March 2024 to examine the complex interactions among biological variables and these factors and their impact on cancer-related health outcomes and health equity.